Hemihypertrophy

What is hemihypertrophy?

Hemihypertrophy, also called hemihyperplasia, is a type of overgrowth syndrome. It is a condition in which one side of the body is bigger than the other. The condition can affect the whole side of the body or just one part of one side of the body, such as the arms, legs or face. The overgrowth in the affected parts of the body can range from mild to severe.

Hemihypertrophy can occur on its own or occur as part of another condition, such as Beckwith-Wiedemann syndrome or Klippel-Trenaunay syndrome. Children with hemihypertrophy may have a higher risk of some types of tumors, including Wilms tumor and hepatoblastoma, a type of liver tumor.

What are the signs and symptoms of hemihypertrophy?

The main symptom of hemihypertrophy is that one side of the body is larger than the other. Sometimes the symptoms may be obvious at birth, but they may not develop until the child is older. Symptoms may get more noticeable over time. If the overgrowth occurs on one side of the face, it can affect chewing and breathing.

What causes hemihypertrophy?

Experts are not sure what causes hemihypertrophy when it occurs on its own. In some cases, it is caused by another condition or syndrome.

How is hemihypertrophy treated?

There is no cure for hemihypertrophy, but treatments are focused on relieving symptoms and addressing any concerns about appearance. Your care team at Arkansas Children’s is experienced in treating hemihypertrophy and will work with you to create the best treatment plan for your child.

Treatment options may include:

• Removal of extra skin or fat with suction
• Surgery to contour or reshape facial bones